BI 167107

Research use only, not for human use.

BI 167107 is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM).

BI 167107 is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM); due to its high potency and slow dissociation from the target BI-167107 was subsequently used to support crystallization of active state β2AR and β2AR-G-protein complexes.

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BI167107

Angiogenesis

Adrenergic Receptor

Adrenergic Receptor

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1202235-68-4

370.449

C21H26N2O4

>98% (HPLC)

In Vitro:?DMSO : 75 mg/mL (202.46 mM)

O=C(N1)COC2=C1C(O)=CC=C2C(CNC(C)(C)CC3=C(C)C=CC=C3)O

5-hydroxy-8-(1-hydroxy-2-((2-methyl-1-(o-tolyl)propan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(-20℃)

With Ice Pack

≥ 2 years